Whole Blood Transcriptomics in Cardiac Surgery Identifies a Gene Regulatory Network Connecting Ischemia Reperfusion with Systemic Inflammation

BACKGROUND: Cardiac surgery with cardiopulmonary bypass (CS/CPB) is associated with increased risk for postoperative complications causing substantial morbidity and mortality. To identify the molecular mechanisms underlying CS/CPB-induced pathophysiology we employed an integrative systems biology ap...

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Hauptverfasser: Liangos, Orfeas, Domhan, Sophie, Schwager, Christian, Zeier, Martin, Huber, Peter E., Addabbo, Francesco, Goligorsky, Michael S., Hlatky, Lynn, Jaber, Bertrand L., Abdollahi, Amir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965092/
https://ncbi.nlm.nih.gov/pubmed/21048961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013658
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