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Pregnancy immunogenetics: NK cell education in the womb?

During embryo implantation and initiation of pregnancy, uterine NK (uNK) cells engage invasive fetal trophoblasts to remodel vessels that conduct blood to the placenta. This partnership, involving uNK cell receptors that recognize HLA-C ligands on trophoblasts, varies the course of human pregnancy b...

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Autores principales: Parham, Peter, Guethlein, Lisbeth A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964998/
https://ncbi.nlm.nih.gov/pubmed/20972330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44559
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