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Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice
The mammalian target of rapamycin (mTOR) is a signaling molecule that senses environmental cues, such as nutrient status and oxygen supply, to regulate cell growth, proliferation, and other functions. Unchecked, sustained mTOR activity results in defects in HSC function. Inflammatory conditions, suc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964994/ https://ncbi.nlm.nih.gov/pubmed/20972332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43873 |
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