The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration

The active thyroid hormone 3,5,3′ triiodothyronine (T3) is a major regulator of skeletal muscle function. The deiodinase family of enzymes controls the tissue-specific activation and inactivation of the prohormone thyroxine (T4). Here we show that type 2 deiodinase (D2) is essential for normal mouse...

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Detalhes bibliográficos
Main Authors: Dentice, Monica, Marsili, Alessandro, Ambrosio, Raffaele, Guardiola, Ombretta, Sibilio, Annarita, Paik, Ji-Hye, Minchiotti, Gabriella, DePinho, Ronald A., Fenzi, Gianfranco, Larsen, P. Reed, Salvatore, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964991/
https://ncbi.nlm.nih.gov/pubmed/20978344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43670
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