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Regulation of the Hypothalamic-Pituitary-Adrenal Axis Circadian Rhythm by Endocannabinoids Is Sexually Diergic

We have examined the effects of acute administration of the cannabinoid receptor type 1 (CB(1)) antagonist AM251 on the rat hypothalamic-pituitary-adrenal (HPA) axis with respect to both gender and time of day. Blood samples were collected from conscious male and female rats every 5 min using an aut...

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Autors principals: Atkinson, Helen C., Leggett, James D., Wood, Susan A., Castrique, Emma S., Kershaw, Yvonne M., Lightman, Stafford L.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964781/
https://ncbi.nlm.nih.gov/pubmed/20534730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0101
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