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Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

Alternative splicing of mRNA precursors is a nearly ubiquitous and extremely flexible point of gene control in humans. It provides cells with the opportunity to create protein isoforms of differing, even opposing, functions from a single gene. Cancer cells often take advantage of this flexibility to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: David, Charles J., Manley, James L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964746/
https://ncbi.nlm.nih.gov/pubmed/21041405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1973010
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