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Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes

BACKGROUND: Lymphatic filariasis and onchocerciasis are debilitating diseases caused by filarial nematodes. Disease pathogenesis is induced by inflammatory responses following the death of the parasite. Wolbachia endosymbionts of filariae are potent inducers of innate and adaptive inflammation and b...

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Autori principali: Johnston, Kelly L, Wu, Bo, Guimarães, Ana, Ford, Louise, Slatko, Barton E, Taylor, Mark J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964653/
https://ncbi.nlm.nih.gov/pubmed/20946650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-3-99
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