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Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes

BACKGROUND: Lymphatic filariasis and onchocerciasis are debilitating diseases caused by filarial nematodes. Disease pathogenesis is induced by inflammatory responses following the death of the parasite. Wolbachia endosymbionts of filariae are potent inducers of innate and adaptive inflammation and b...

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Bibliographische Detailangaben
Hauptverfasser: Johnston, Kelly L, Wu, Bo, Guimarães, Ana, Ford, Louise, Slatko, Barton E, Taylor, Mark J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964653/
https://ncbi.nlm.nih.gov/pubmed/20946650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-3-99
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