Human immunodeficiency virus-1 infection of macrophages in vitro neither induces tumor necrosis factor (TNF)/cachectin gene expression nor alters TNF/cachectin induction by lipopolysaccharide.

The synthesis of tumor necrosis factor (TNF)/cachectin was assessed in primary monocyte-derived macrophage (MDM) cultures after in vitro infection with a macrophage-tropic strain of HIV-1 (HTLV-IIIBa-L/85). Productive and cytopathic infections in MDM cultures were established using a high multiplici...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Munis, J R, Richman, D D, Kornbluth, R S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296464/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2298923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114478
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