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PDGF-B-driven gliomagenesis can occur in the absence of the proteoglycan NG2
BACKGROUND: In the last years, the transmembrane proteoglycan NG2 has gained interest as a therapeutic target for the treatment of diverse tumor types, including gliomas, because increases of its expression correlate with dismal prognosis. NG2 has been shown to function as a co-receptor for PDGF lig...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964636/ https://ncbi.nlm.nih.gov/pubmed/20939912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-550 |
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