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Disrupted postnatal lung development in heme oxygenase-1 deficient mice

BACKGROUND: Heme oxygenase (HO) degrades cellular heme to carbon monoxide, iron and biliverdin. The HO-1 isoform is both inducible and cyto-protective during oxidative stress, inflammation and lung injury. However, little is known about its precise role and function in lung development. We hypothesi...

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Bibliografische gegevens
Hoofdauteurs: Zhuang, Tiangang, Zhang, Monica, Zhang, Huayan, Dennery, Phyllis A, Lin, Qing S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964616/
https://ncbi.nlm.nih.gov/pubmed/20932343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-142
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