Therapeutic efficacy of alpha-1 antitrypsin augmentation therapy on the loss of lung tissue: an integrated analysis of 2 randomised clinical trials using computed tomography densitometry

BACKGROUND: Two randomised, double-blind, placebo-controlled trials have investigated the efficacy of IV alpha-1 antitrypsin (AAT) augmentation therapy on emphysema progression using CT densitometry. METHODS: Data from these similar trials, a 2-center Danish-Dutch study (n = 54) and the 3-center EXA...

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Detalhes bibliográficos
Main Authors: Stockley, Robert A, Parr, David G, Piitulainen, Eeva, Stolk, Jan, Stoel, Berend C, Dirksen, Asger
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964614/
https://ncbi.nlm.nih.gov/pubmed/20920370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-136
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