HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

Myeloid-derived suppressor cells (MDSCs) are a major component of the immune-suppressive network described in cancer and many other pathological conditions. We demonstrate that although MDSCs from peripheral lymphoid organs and the tumor site share similar phenotype and morphology, these cells displ...

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Autori principali: Corzo, Cesar A., Condamine, Thomas, Lu, Lily, Cotter, Matthew J., Youn, Je-In, Cheng, Pingyan, Cho, Hyun-Il, Celis, Esteban, Quiceno, David G., Padhya, Tapan, McCaffrey, Thomas V., McCaffrey, Judith C., Gabrilovich, Dmitry I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964584/
https://ncbi.nlm.nih.gov/pubmed/20876310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100587
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