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The innate immune system in host mice targets cells with allogenic mitochondrial DNA

Mitochondrial DNA (mtDNA) has been proposed to be involved in respiratory function, and mtDNA mutations have been associated with aging, tumors, and various disorders, but the effects of mtDNA imported into transplants from different individuals or aged subjects have been unclear. We examined this i...

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Detalhes bibliográficos
Main Authors: Ishikawa, Kaori, Toyama-Sorimachi, Noriko, Nakada, Kazuto, Morimoto, Mami, Imanishi, Hirotake, Yoshizaki, Mariko, Sasawatari, Shigemi, Niikura, Mamoru, Takenaga, Keizo, Yonekawa, Hiromichi, Hayashi, Jun-Ichi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964578/
https://ncbi.nlm.nih.gov/pubmed/20937705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092296
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