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Rapid topology probing using fluorescence spectroscopy in planar lipid bilayer: the pore-forming mechanism of the toxin Cry1Aa of Bacillus thuringiensis

Pore-forming toxins, many of which are pathogenic to humans, are highly dynamic proteins that adopt a different conformation in aqueous solution than in the lipid environment of the host membrane. Consequently, their crystal structures obtained in aqueous environment do not reflect the active confor...

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Detalhes bibliográficos
Main Authors: Groulx, Nicolas, Juteau, Marc, Blunck, Rikard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964520/
https://ncbi.nlm.nih.gov/pubmed/20974771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910347
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