Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro.
Bisphosphonates are useful in treatment of disorders with increased osteoclastic activity, but the mechanism by which bisphosphonates act is unknown. We used cultures of chicken osteoclasts to address this issue, and found that 1-hydroxyethylidenediphosphonic acid (EHDP), dichloromethylidenediphosph...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
1990
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296445/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2105340/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114459 |
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