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Suppression of interleukin 2-dependent human T cell growth in vitro by prostaglandin E (PGE) and their precursor fatty acids. Evidence for a PGE-independent mechanism of inhibition by the fatty acids.

PGE represent oxygenation products of polyunsaturated essential fatty acids and are important regulators of cell-mediated immune responses. Because oils enriched in such fatty acids reduce inflammation and tissue injury in vivo, we examined the effects of these PGE precursors on IL-2-driven growth o...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Santoli, D, Phillips, P D, Colt, T L, Zurier, R B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296441/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2298918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114455
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