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The bridge-region of the Ku superfamily is an atypical zinc ribbon domain

Members of the Ku superfamily are DNA-end-binding proteins involved in non-homologous end-joining (NHEJ) DNA repair. The published crystal structure of human Ku-DNA complex reveals a heterodimer that forms a ring around dsDNA by means of the Ku core modules. These modules contain a highly conserved...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Krishna, S. Sri, Aravind, L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964384/
https://ncbi.nlm.nih.gov/pubmed/20580930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2010.05.011
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