Interleukin-27, an Anti-HIV-1 Cytokine, Inhibits Replication of Hepatitis C Virus

Interleukin (IL)-27 is a member of IL-12 family cytokine. We have previously reported that IL-27 inhibits human immunodeficiency virus type-1 (HIV-1) replication in CD4(+) T cells and monocyte-derived macrophages, even though IL-12 enhances HIV-1 replication in primary CD4(+) T cells. Further study...

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Bibliographic Details
Main Authors: Frank, Astrid C., Zhang, Xiaozhen, Katsounas, Antonios, Bharucha, Jennifer P., Kottilil, Shyamasundaran, Imamichi, Tomozumi
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2010
Subjects:
Research Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964364/
https://ncbi.nlm.nih.gov/pubmed/20235668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2009.0093
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