iCLIP Predicts the Dual Splicing Effects of TIA-RNA Interactions

The regulation of alternative splicing involves interactions between RNA-binding proteins and pre-mRNA positions close to the splice sites. T-cell intracellular antigen 1 (TIA1) and TIA1-like 1 (TIAL1) locally enhance exon inclusion by recruiting U1 snRNP to 5′ splice sites. However, effects of TIA...

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Main Authors: Wang, Zhen, Kayikci, Melis, Briese, Michael, Zarnack, Kathi, Luscombe, Nicholas M., Rot, Gregor, Zupan, Blaž, Curk, Tomaž, Ule, Jernej
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964331/
https://ncbi.nlm.nih.gov/pubmed/21048981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000530
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