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Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence

The brain is not routinely surveyed by lymphocytes and is defined as an immuno-privileged site. However, viral infection of the brain results in the infiltration and long-term persistence of pathogen-specific CD8(+) T cells. These cells survive without replenishment from the circulation and are refe...

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Detalhes bibliográficos
Main Authors: Wakim, Linda M., Woodward-Davis, Amanda, Bevan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964240/
https://ncbi.nlm.nih.gov/pubmed/20923878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010201107
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