Structures of aminoacylase 3 in complex with acetylated substrates

Trichloroethylene (TCE) is one of the most widespread environmental contaminants, which is metabolized to N-acetyl-S-1,2-dichlorovinyl-l-cysteine (NA-DCVC) before being excreted in the urine. Alternatively, NA-DCVC can be deacetylated by aminoacylase 3 (AA3), an enzyme that is highly expressed in th...

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Bibliografiska uppgifter
Huvudupphovsmän: Hsieh, Jennifer M., Tsirulnikov, Kirill, Sawaya, Michael R., Magilnick, Nathaniel, Abuladze, Natalia, Kurtz, Ira, Abramson, Jeff, Pushkin, Alexander
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964198/
https://ncbi.nlm.nih.gov/pubmed/20921362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006687107
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