Candidate Single Nucleotide Polymorphism Markers for Arsenic Responsiveness of Protein Targets

Arsenic is a toxic metalloid that causes skin cancer and binds to cysteine residues—a property that could be used to infer arsenic responsiveness of a target protein. Non-synonymous Single Nucleotide Polymorphisms (nsSNPs) result in amino acid substitutions and may alter arsenic binding with cystein...

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Main Authors: Isokpehi, Raphael D., Cohly, Hari H.P., Anyanwu, Matthew N., Rajnarayanan, Rajendram V., Tchounwou, Paul B., Udensi, Udensi K., Graham-Evans, Barbara E.
Format: Artigo
Sprog:Inglês
Udgivet: Libertas Academica 2010
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964045/
https://ncbi.nlm.nih.gov/pubmed/20981267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BBI.S5498
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