Effects of Rapamycin on Cultured Hepatocyte Proliferation and Gene Expression

Rapamycin, a potent immunosuppressive drug that disrupts normal signal-transduction processes, inhibited hepatocyte proliferation without evidence of inherent cytotoxicity in rat hepatocytes cultured in conventional medium or in a medium enriched with epidermal growth factor. The antiproliferative e...

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Main Authors: Francavilla, Antonio, Carr, Brian I., Starzl, Thomas E., Azzarone, Alessandro, Carrieri, Giuseppe, Zeng, Qui-Hua
Format: Artigo
Language:Inglês
Published: 1992
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963996/
https://ncbi.nlm.nih.gov/pubmed/1568729
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