B-cell depletion reveals a role for antibodies in the control of chronic HIV-1 infection

HIV can be partially contained by host immunity and understanding the basis of this may inform vaccine design. The importance of B-cell function in long-term control is poorly understood. One method of investigating this is in vivo cellular depletion. In this study, we take advantage of a unique opp...

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Hlavní autoři: Huang, Kuan-Hsiang G., Bonsall, David, Katzourakis, Aris, Thomson, Emma C., Fidler, Sarah J., Main, Janice, Muir, David, Weber, Jonathan N., Frater, Alexander J., Phillips, Rodney E., Pybus, Oliver G., Goulder, Philip J.R., McClure, Myra O., Cooke, Graham S., Klenerman, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963804/
https://ncbi.nlm.nih.gov/pubmed/20981030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1100
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