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Individual (N-of-1) trials can be combined to give population comparative treatment effect estimates: Methodologic considerations
OBJECTIVE: To compare different statistical models for combining N-of-1 trials to estimate a population treatment effect. STUDY DESIGN AND SETTING: Data from a published series of N-of-1 trials comparing amitriptyline therapy and combination treatment (amitriptyline + fluoxetine ) were analyzed to c...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963698/ https://ncbi.nlm.nih.gov/pubmed/20863658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2010.04.020 |
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