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Individual (N-of-1) trials can be combined to give population comparative treatment effect estimates: Methodologic considerations

OBJECTIVE: To compare different statistical models for combining N-of-1 trials to estimate a population treatment effect. STUDY DESIGN AND SETTING: Data from a published series of N-of-1 trials comparing amitriptyline therapy and combination treatment (amitriptyline + fluoxetine ) were analyzed to c...

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Detalhes bibliográficos
Main Authors: Zucker, Deborah R., Ruthazer, Robin, Schmid, Christopher H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963698/
https://ncbi.nlm.nih.gov/pubmed/20863658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2010.04.020
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