Profilin-1 Is Expressed in Human Atherosclerotic Plaques and Induces Atherogenic Effects on Vascular Smooth Muscle Cells

BACKGROUND: Profilin-1 is an ubiquitous actin binding protein. Under pathological conditions such as diabetes, profilin-1 levels are increased in the vascular endothelium. We recently demonstrated that profilin-1 overexpression triggers indicators of endothelial dysfunction downstream of LDL signali...

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Main Authors: Caglayan, Evren, Romeo, Giulio R., Kappert, Kai, Odenthal, Margarete, Südkamp, Michael, Body, Simon C., Shernan, Stanton K., Hackbusch, Daniel, Vantler, Marius, Kazlauskas, Andrius, Rosenkranz, Stephan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963617/
https://ncbi.nlm.nih.gov/pubmed/21049052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013608
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