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Cell Surface Restriction of EGFR by a Tenascin Cytotactin-Encoded EGF-Like Repeat Is Preferential for Motility-Related Signaling
The 14th EGFL-repeat (Ten14) of human tenascin cytotactin activates the epidermal growth factor receptor (EGFR) with micromolar affinity; however, unlike EGF, Ten14-mediated activation of EGFR does not lead to receptor internalization. As the divergent signaling pathways downstream of EGFR have been...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963575/ https://ncbi.nlm.nih.gov/pubmed/17708541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21232 |
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