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Kinetics of Re-establishing H3K79 Methylation Marks in Global Human Chromatin

We employ a stable isotope strategy wherein both histones and their methylations are labeled in synchronized human cells. This allows us to differentiate between old and new methylations on pre-existing versus newly synthesized histones. The strategy is implemented on K79 methylation in an isoform-s...

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Detalhes bibliográficos
Main Authors: Sweet, Steve M. M., Li, Mingxi, Thomas, Paul M., Durbin, Kenneth R., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963384/
https://ncbi.nlm.nih.gov/pubmed/20699226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.145094
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