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Hyperphosphorylation by Cyclin B/CDK1 in Mitosis Resets CUX1 DNA Binding Clock at Each Cell Cycle

The p110 CUX1 homeodomain protein participates in the activation of DNA replication genes in part by increasing the affinity of E2F factors for the promoters of these genes. CUX1 expression is very weak in quiescent cells and increases during G(1). Biochemical activities associated with transcriptio...

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Main Authors: Sansregret, Laurent, Gallo, David, Santaguida, Marianne, Leduy, Lam, Harada, Ryoko, Nepveu, Alain
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963374/
https://ncbi.nlm.nih.gov/pubmed/20729212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.156406
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