Factors from Human Embryonic Stem Cell-derived Fibroblast-like Cells Promote Topology-dependent Hepatic Differentiation in Primate Embryonic and Induced Pluripotent Stem Cells

The future clinical use of embryonic stem cell (ESC)-based hepatocyte replacement therapy depends on the development of an efficient procedure for differentiation of hepatocytes from ESCs. Here we report that a high density of human ESC-derived fibroblast-like cells (hESdFs) supported the efficient...

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Main Authors: Huang, Hsiang-Po, Yu, Chun-Ying, Chen, Hsin-Fu, Chen, Pin-Hsun, Chuang, Ching-Yu, Lin, Sung-Jan, Huang, Shih-Tsung, Chan, Wei-Hung, Ueng, Tzuu-Huei, Ho, Hong-Nerng, Kuo, Hung-Chih
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963358/
https://ncbi.nlm.nih.gov/pubmed/20720011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.122093
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