Binding of Toxoplasma gondii Glycosylphosphatidylinositols to Galectin-3 Is Required for Their Recognition by Macrophages

We showed that the production of tumor necrosis factor (TNF) α by macrophages in response to Toxoplasma gondii glycosylphosphatidylinositols (GPIs) requires the expression of both Toll-like receptors TLR2 and TLR4, but not of their co-receptor CD14. Galectin-3 is a β-galactoside-binding protein with...

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Main Authors: Debierre-Grockiego, Françoise, Niehus, Sebastian, Coddeville, Bernadette, Elass, Elisabeth, Poirier, Françoise, Weingart, Ralf, Schmidt, Richard R., Mazurier, Joël, Guérardel, Yann, Schwarz, Ralph T.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
主題:
Glycobiology and Extracellular Matrices
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963347/
https://ncbi.nlm.nih.gov/pubmed/20729207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.137588
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