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Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma.
The insulin-like growth factor II (IGF2) gene is exclusively silent at the maternal allele in the mouse as well as in normal human tissues and is expressed at a high level in rhabdomyosarcoma (RMS). We report here that the normally imprinted allele of the IGF2 gene is activated in RMS tumors as well...
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Главные авторы: | , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
1994
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC296329/ https://ncbi.nlm.nih.gov/pubmed/8040287 |
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