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A comparison of the antiatherogenic effects of probucol and of a structural analogue of probucol in low density lipoprotein receptor-deficient rabbits.

The efficacies of probucol and a close structural analogue as antioxidants in the prevention of atherogenesis in LDL receptor-deficient rabbits were compared. The antioxidant potency of the analogue in vitro was equal to that of probucol. Its biological availability was much greater: almost comparab...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Fruebis, J, Steinberg, D, Dresel, H A, Carew, T E
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296321/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040279/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117334
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