Pathogenesis of periodontitis: a major arginine-specific cysteine proteinase from Porphyromonas gingivalis induces vascular permeability enhancement through activation of the kallikrein/kinin pathway.

To elucidate the mechanism of production of an inflammatory exudate, gingival crevicular fluid (GCF), from periodontal pockets in periodontitis, we examined the vascular permeability enhancement (VPE) activity induced by an arginine-specific cysteine proteinase, Arg-gingipain-1 (RGP-1), produced by...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Imamura, T, Pike, R N, Potempa, J, Travis, J
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1994
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040277/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117330
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