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Selenium-Containing Analogs of SAHA Induce Cytotoxicity in Lung Cancer Cells

Cancer therapy has moved beyond conventional chemotherapeutics to more mechanism-based targeted approaches. Studies demonstrate that histone deacetylase (HDAC) is a promising target for anticancer agents. Numerous, structurally diverse, hydroxamic acid derivative, HDAC inhibitors have been reported...

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Bibliografische gegevens
Hoofdauteurs: Karelia, Nilkamal, Desai, Dhimant, Hengst, Jeremy A., Amin, Shantu, Rudrabhatla, Sairam V., Yun, Jong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963109/
https://ncbi.nlm.nih.gov/pubmed/20855208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.08.113
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