Development of Spontaneous Anergy in Invariant Natural Killer T Cells in a Mouse Model of Dyslipidemia

OBJECTIVE: In this study, we investigated whether dyslipidemia-associated perturbed invariant natural killer T (iNKT) cell function is due to intrinsic changes in iNKT cells or defects in the ability of antigen-presenting cells to activate iNKT cells. METHODS AND RESULTS: We compared iNKT cell expan...

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Main Authors: Braun, Nicole A., Mendez-Fernandez, Yanice V., Covarrubias, Roman, Porcelli, Steven A., Savage, Paul B., Yagita, Hideo, Van Kaer, Luc, Major, Amy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963029/
https://ncbi.nlm.nih.gov/pubmed/20539017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.206045
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