Rapid Gynogenetic Mapping of Xenopus tropicalis Mutations to Chromosomes

Pilot forward genetic screens in Xenopus tropicalis have isolated over 60 recessive mutations (Grammer et al., 2005; Noramly et al., 2005; Goda et al., 2006). Here we present a simple method for mapping mutations to chromosomes using gynogenesis and centromeric markers. When coupled with available g...

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Autors principals: Khokha, Mustafa K., Krylov, Vladimir, Reilly, Michael J., Gall, Joseph G., Bhattacharya, Dipankan, Cheung, Chung Yan J., Kaufman, Sarah, Lam, Dang Khoa, Macha, Jaroslav, Ngo, Catherine, Prakash, Neha, Schmidt, Philip, Tlapakova, Tereza, Trivedi, Toral, Tumova, Lucie, Abu-Daya, Anita, Geach, Timothy, Vendrell, Elisenda, Ironfield, Holly, Sinzelle, Ludivine, Sater, Amy K., Wells, Dan E., Harland, Richard M., Zimmerman, Lyle B.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962985/
https://ncbi.nlm.nih.gov/pubmed/19441086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21965
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