Stimulation with type I collagen induces changes in gene expression in peripheral blood mononuclear cells from patients with diffuse cutaneous systemic sclerosis (scleroderma)

An autoantigenic role for collagen type I (CI) has been suggested previously in diffuse cutaneous systemic sclerosis (dcSSc). Whether CI is indeed capable of affecting the immune system in dcSSc is not known. Patients with early (3 years or less) or late (>3 years) dcSSc and healthy controls dona...

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Autori principali: Atamas, S P, Luzina, I G, Ingels, J, Choi, J, Wong, W K, Furst, D E, Clements, P J, Postlethwaite, A E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2010
Soggetti:
Translational Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962959/
https://ncbi.nlm.nih.gov/pubmed/20529088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04189.x
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