Tumor necrosis factor-alpha inhibits stem cell factor-induced proliferation of human bone marrow progenitor cells in vitro. Role of p55 and p75 tumor necrosis factor receptors.

Stem cell factor (SCF), a key regulator of hematopoiesis, potently synergizes with a number of hematopoietic growth factors. However, little is known about growth factors capable of inhibiting the actions of SCF. TNF-alpha has been shown to act as a bidirectional regulator of myeloid cell proliferat...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Rusten, L S, Smeland, E B, Jacobsen, F W, Lien, E, Lesslauer, W, Loetscher, H, Dubois, C M, Jacobsen, S E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296294/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518828/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117303
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