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Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. I. Is the extent of atherosclerosis related to resistance of LDL to oxidation?

Lipoprotein oxidation is believed to play an important role in atherogenesis. To investigate whether inhibition of oxidation of low density lipoprotein (LDL) would alter atherogenesis in the nonhuman primate, we administered probucol, a potent antioxidant, to Macaca nemestrina fed a high-fat, high-c...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Sasahara, M, Raines, E W, Chait, A, Carew, T E, Steinberg, D, Wahl, P W, Ross, R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117301
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