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Attenuation of streptozotocin-induced microvascular changes in the mouse retina with the endothelin receptor A antagonist atrasentan

Hyperglycemia mediates endothelial cell dysfunction through a number of potential mechanisms that could result in the decrease of retinal blood flow early in diabetes. The aim of this study was to explore the role of endothelin receptor A (ET(A)) in the early decrease of retinal blood flow in diabet...

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Main Authors: Wang, Zhongli, Yadav, Amit Singh, Leskova, Wendy, Harris, Norman R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962698/
https://ncbi.nlm.nih.gov/pubmed/20727883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2010.08.008
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