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Development of a Low Bias Method for Characterizing Viral Populations Using Next Generation Sequencing Technology

BACKGROUND: With an estimated 38 million people worldwide currently infected with human immunodeficiency virus (HIV), and an additional 4.1 million people becoming infected each year, it is important to understand how this virus mutates and develops resistance in order to design successful therapies...

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Bibliographische Detailangaben
Hauptverfasser: Willerth, Stephanie M., Pedro, Hélder A. M., Pachter, Lior, Humeau, Laurent M., Arkin, Adam P., Schaffer, David V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962647/
https://ncbi.nlm.nih.gov/pubmed/21042592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013564
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