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The Clathrin Assembly Protein AP180 Regulates the Generation of Amyloid-β Peptide

The overproduction and extracellular buildup of amyloid-β peptide (Aβ) is a critical step in the etiology of Alzheimer’s disease. Recent data suggest that intracellular trafficking is of central importance in the production of Aβ. Here we use a neuronal cell line to examine two structurally similar...

詳細記述

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書誌詳細
主要な著者: Wu, Fangbai, Matsuoka, Yasuji, Mattson, Mark P., Yao, Pamela J.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962620/
https://ncbi.nlm.nih.gov/pubmed/19450545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.050
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