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The Clathrin Assembly Protein AP180 Regulates the Generation of Amyloid-β Peptide
The overproduction and extracellular buildup of amyloid-β peptide (Aβ) is a critical step in the etiology of Alzheimer’s disease. Recent data suggest that intracellular trafficking is of central importance in the production of Aβ. Here we use a neuronal cell line to examine two structurally similar...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2962620/ https://ncbi.nlm.nih.gov/pubmed/19450545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.050 |
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