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Streptogramin- and tetracycline-responsive dual regulated expression of p27(Kip1) sense and antisense enables positive and negative growth control of Chinese hamster ovary cells

We constructed a dual regulated expression vector cassette (pDuoRex) whereby two heterologous genes can be independently regulated via streptogramin- and tetracycline-responsive promoters. Two different constructs containing growth-promoting and growth-inhibiting genes were stably transfected in rec...

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Detalhes bibliográficos
Main Authors: Fux, Cornelia, Moser, Samuel, Schlatter, Stefan, Rimann, Markus, Bailey, James E., Fussenegger, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC29626/
https://ncbi.nlm.nih.gov/pubmed/11160939
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