Recombinant Membrane-targeted Form of CD59 Inhibits the Growth of Choroidal Neovascular Complex in Mice

This study was designed to explore the effect of recombinant, membrane-targeted CD59 (rCD59-APT542) on the growth and size of fully developed neovascular complex using the murine model of laser-induced choroidal neovascularization (CNV). CNV was induced by laser photocoagulation in C57BL/6 mice usin...

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Autores principales: Bora, Nalini S., Jha, Purushottam, Lyzogubov, Valeriy V., Kaliappan, Sankaranarayanan, Liu, Juan, Tytarenko, Ruslana G., Fraser, Deborah A., Morgan, B. Paul, Bora, Puran S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962482/
https://ncbi.nlm.nih.gov/pubmed/20736175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.153130
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