The CroRS Two-Component Regulatory System Is Required for Intrinsic β-Lactam Resistance in Enterococcus faecalis

Enterococcus faecalis produces a specific penicillin-binding protein (PBP5) that mediates high-level resistance to the cephalosporin class of β-lactam antibiotics. Deletion of a locus encoding a previously uncharacterized two-component regulatory system of E. faecalis (croRS) led to a 4,000-fold red...

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Autors principals: Comenge, Yannick, Quintiliani, Richard, Li, Ling, Dubost, Lionnel, Brouard, Jean-Paul, Hugonnet, Jean-Emmanuel, Arthur, Michel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC296236/
https://ncbi.nlm.nih.gov/pubmed/14645279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.24.7184-7192.2003
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