Single and Double Mutations in gyrA but Not in gyrB Are Associated with Low- and High-Level Fluoroquinolone Resistance in Helicobacter pylori

In one French hospital the rate of resistance to ciprofloxacin in Helicobacter pylori was 3.3% (2 of 60 strains) in 1999. The six resistant clinical strains (four from 1996 and two from 1999) and three ciprofloxacin-selected single-step mutants studied carried one gyrA mutation but none in gyrB. Cli...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Tankovic, Jacques, Lascols, Christine, Sculo, Quentin, Petit, Jean-Claude, Soussy, Claude-James
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296230/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638505/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3942-3944.2003
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