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Plasmid DNA delivery into MDA-MB-453 cells mediated by recombinant Her-NLS fusion protein

A major rate-limiting step in nonviral gene delivery is the entry of nucleic acids across various membrane barriers and eventually into the nucleus where it must be transcribed. Cell-penetrating peptides and proteins are employed to generate formulations that overcome these challenges to facilitate...

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Detalhes bibliográficos
Main Authors: Jeyarajan, Sivakumar, Xavier, Jennifer, Rao, N Madhusudhana, Gopal, Vijaya
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962268/
https://ncbi.nlm.nih.gov/pubmed/21042418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S13040
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