In Vivo Efficacy of a New Quinolone, DQ-113, against Streptococcus pneumoniae in a Mouse Model

DQ-113 is a new quinolone with potent activity against gram-positive pathogens. The in vivo activity of DQ-113 against Streptococcus pneumoniae was compared with those of gatifloxacin and ciprofloxacin in a mouse model. For this purpose, two strains of S. pneumoniae were used: penicillin-susceptible...

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Detalhes bibliográficos
Main Authors: Otsu, Yoshiko, Yanagihara, Katsunori, Fukuda, Yuichi, Miyazaki, Yoshitsugu, Tsukamoto, Kazuhiro, Hirakata, Yoichi, Tomono, Kazunori, Kadota, Jun-ichi, Tashiro, Takayoshi, Murata, Ikuo, Kohno, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC296211/
https://ncbi.nlm.nih.gov/pubmed/14638468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.12.3699-3703.2003
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